Karzan is a University Teacher in Orthoptics at the University of Sheffield. He is a co-author on the Curriculum Framework for Pre-registration Orthoptic Education and Training. With over a decade of clinical experience, he has a specialist interest in stroke & neuro-rehabilitation. He has honorary clinical contracts at the Royal Hallamshire Hospital in Sheffield, and Salford Royal Hospital, Greater Manchester. Karzan leads the Medicines Clinical Advisory Group for the British and Irish Orthoptic Society. He is actively involved in raising the standards of medicinal practice within the profession and leads the campaign for Orthoptists to expand into independent prescribing.